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Tetrabutylammonium Fluoride Trihydrate

Name: Tetrabutylammonium Fluoride Trihydrate
Brand: TRIVENI INTERCHEM PVT. LTD.
Price: 8000.0 INR
Availability: InStock

Price 8000.0 INR/ Kilograms

Get a Price/Quote

MOQ : 25 Kilograms

Tetrabutylammonium Fluoride Trihydrate Specification

Molecular Formula
[CH3(CH2)3]4NF 3H2O

Usage
Phase-transfer catalyst and fluoride source in organic synthesis; deprotection of silyl ethers

Purity
98 99%

Structural Formula
[CH3(CH2)3]4NF 3H2O

Refractive Rate
1.5

Solubility
Soluble in water and polar solvents; insoluble in nonpolar solvents

Properties
Tetrabutylammonium fluoride trihydrate is a widely used fluoride source in organic synthesis. It is particularly valued for its ability to desilylate silyl ethers, acting as a crucial tool for removing protecting groups. Its hydrate form is easier to handle and more stable than the highly hygroscopic anhydrous version.

CAS No
87749-50-6

Molecular Weight
315.51 g/mol Grams (g)

Physical Form
Solid

Appearance
White crystalline solid

Application
Industrial

Melting Point
68 C

Tetrabutylammonium Fluoride Trihydrate Trade Information

Minimum Order Quantity
25 Kilograms

Payment Terms
Cash in Advance (CID)

Supply Ability
5000 Kilograms Per Month

Delivery Time
10 Days

Main Domestic Market
All India

About Tetrabutylammonium Fluoride Trihydrate

We are Supplier, Exporter and Contract Manufacturer.

Technical profile of Tetrabutylammonium Fluoride Trihydrate, a high-purity raw chemical material supplied by Triveni Chemicals for industrial manufacturing and laboratory synthesis.

Technical Specifications:

CAS Number: 87749-50-6

Chemical Formula: [CH3(CH2)3]4NF 3H2O

Industrial Uses & Applications:

It Appears As A White To Off White Crystalline Solid And Is Soluble In Water And Polar Organic Solvents. The Trihydrate Form Is More Stable And Easier To Handle Than The Anhydrous Grade. Tbaf Trihydrate Is Widely Used In Organic Synthesis As A Fluoride Ion Source, Especially For The Removal Of Silyl Protecting Groups.

Versatile Reagent for Organic Synthesis

Tetrabutylammonium Fluoride Trihydrate stands out as a preferred reagent for chemists working on complex organic transformations. Its excellent solubility in polar solvents and high fluoride ion reactivity enable efficient deprotection of silyl ethers and various other organic syntheses. Additionally, its solid, hydrated form minimizes handling challenges associated with hygroscopic materials.

Enhanced Stability and Safety

The trihydrate crystal structure of this compound ensures more secure storage and handling compared to the anhydrous form, which readily absorbs moisture and can be difficult to manage. This stability increases both safety and efficiency in laboratory and industrial settings, reducing waste and simplifying workflows.

FAQ's of Tetrabutylammonium Fluoride Trihydrate:

Q: How is Tetrabutylammonium Fluoride Trihydrate typically used in industrial applications?

A: It is primarily used as a fluoride source and a phase-transfer catalyst in organic synthesis. The compound is especially valued for efficiently removing silyl ether protecting groups during synthetic processes.

Q: What advantages does the trihydrate form provide over the anhydrous form?

A: The trihydrate form is significantly easier to handle and more stable. Unlike the anhydrous version, which is highly hygroscopic and can absorb moisture rapidly, the trihydrate resists moisture uptake and remains a manageable solid.

Q: When should Tetrabutylammonium Fluoride Trihydrate be used in organic synthesis?

A: It is best used whenever a mild yet effective fluoride source is required, especially during the deprotection of silyl ethers or when phase-transfer catalysis involving fluoride ions is necessary.

Q: Where can Tetrabutylammonium Fluoride Trihydrate be sourced for industrial use?

A: The compound is manufactured and supplied by various chemical companies in India, with a focus on producing high-purity material suited for industrial and laboratory applications.

Q: What is the process for using this compound as a desilylating agent?

A: Typically, it is dissolved in a polar solvent along with the silyl ether substrate. Upon mixing, the Tetrabutylammonium Fluoride Trihydrate provides fluoride ions that cleave the silyl group, freeing the desired compound.

Q: What benefits does this compound offer for phase-transfer catalysis?

A: Its solubility in polar solvents and the availability of reactive fluoride ions make it an effective agent for facilitating reactions between substances in different phases, improving reaction efficiency and yields.

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