N-Iodosuccinimide (0516-12-1) (C4H4INO2)

About N-Iodosuccinimide (0516-12-1) (C4H4INO2)

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Technical profile of N-Iodosuccinimide, a high-purity raw chemical material supplied by Triveni Chemicals for industrial manufacturing and laboratory synthesis.

N-Iodosuccinimide (NIS) is an iodinating reagent with the chemical formula CHINO and molecular weight 224.98 g/mol. It appears as a white to pale yellow crystalline solid. It is slightly soluble in water and soluble in polar organic solvents such as acetonitrile and DMF. It is stable under dry, cool storage but sensitive to moisture and light.

In terms of uses and applications, N-Iodosuccinimide is widely used in organic synthesis for selective iodination of aromatic compounds, alkenes, alkynes, and heterocycles. It is valuable in the pharmaceutical and fine chemical industries for preparing iodinated intermediates used in drug synthesis. It is also used in glycosylation reactions and halogen-mediated cyclization processes. In research laboratories, it serves as a mild electrophilic iodine source for efficient and controlled reactions. Additionally, it is used in specialty chemical manufacturing where selective iodination is required.